Jovaro wrote:I think Alyrium meaned the study about the increased risk of hepatitis, none of your two links say something about that...
However, many others do. I used bad terminology with "increased risk" since the studies state CCR5 fascilitates HCV.
Taken together, there exist intriguing theoretical concepts as well as first observational evidence to suggest an important role of CCR5 and its ligands with respect to the pathogenesis of HCV infection. However, the available observational data remain controversial at the present stage. Further research in different ethnic populations and consideration of additional genetic markers are needed to understand the role of polymorphic genetic traits in a disease that is of polygenic nature. Furthermore, chronic hepatitis C virus infection may be just a first example for a group of infectious diseases, where alterations in the balance between type 1 and type 2 immune responses may be of importance. Therefore, it should also be worthwhile studying the potential roles of CCR5 and its ligands in other infectious diseases with a putatively altered immune balance such as tuberculosis and leprosy.
http://jac.oupjournals.org/cgi/content/full/53/6/895
Alyrium posted:
DO they? Have a source for this? SOmetimes they increase efficiency, or cause a mutation in the genes that code for CD4 thus granting HIV immunity. Your arguemnt falls flat
One of the sites I cited states the CCR5 mutation has been around at least 800 years so do draw conclusions that HIV infection resulted in this mutation is ludicrous and to use Alyrium's phrase "falls flat".